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ANILINE DERIVATIVES,THEIR PREPARATION AND THEIR TH

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专利名称:ANILINE DERIVATIVES,THEIR PREPARATION

AND THEIR THERAPEUTIC APPLICATION

发明人:FEUTRILL, John,LERICHE,

Caroline,MIDDLEMISS, David

申请号:EP12762245.4申请日:20120907公开号:EP2755944A2公开日:20140723

摘要:The present invention relates to aniline derivatives of formula (I), to theirpreparation and to their therapeutic application, for example in treating glaucoma:Formula (I), R1a represents H, an halogen, a (C1-C6)alkyl or a CN; R1b represents H, anhalogen or a (C1-C6)alkyl; R1c represents H or a (C1-C6)alkyl; R2 represents H, anhalogen, an OH, an O—(C1-C6)alkyl or (C1-C6)alkyl; R3 represents H, an halogen, a (C1-C6)alkyl, an OH, an O—(C1-C6)alkyl, a CONH2 or CN; R4 represents H, an halogen or a(C1-C6)alkyl; R5 represents H or F: R7 represents H or F; R8 represents H or F; R9represents H or (C1-C6)alkyl, or one of its enantiomers.

申请人:Fovea Pharmaceuticals

地址:Institut de la Vision 17 Rue Moreau 75012 Paris FR

国籍:FR

代理机构:Blot, Philippe Robert Emile

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