专利名称：METHOD FOR PREPARING POLYMERIC
MICROSPHERES CONTAINING DRUG
发明人：KIM, Hong Kee,SHIN, Ho Chul,LEE, Yoon-Jung,HONG, Seok Hyun,LEE, Kyu Ho,KIM,Hun-Teak,KWAK, Yong-Kyu
申请号：EP15776327.7申请日：20150407公开号：EP3130333A4公开日：20171122
摘要：The present invention relates to a method for preparing polymeric
microspheres to improve the drug encapsulating efficiency and, more specifically, to amethod for preparing polymeric microspheres, the method comprising the steps of:preparing an internal water phase (w1) and an oil phase (0); mixing the internal waterphase and the oil phase to prepare a W1/0 emulsion, followed by cooling; mixing theW1/0 emulsion with an external water phase (W2) to prepare a W1/0/W2 emulsion; anddrying the prepared W1/0/W2 emulsion, followed by collection. The method of thepresent invention can increase the drug encapsulating efficiency and manufacturepolymeric microspheres having high drug contents through a procedure of maintainingthe step of solidifying the oil phase at a particular temperature for a particular period oftime, and thus the method of the present invention is effective in the preparation ofsustained release-type drugs.
申请人：SK Chemicals Co., Ltd.
地址：Sampyeong-dong 310 Pangyo-ro Bundang-gu Seongnam-si, Gyeonggi-do 463-
400 KR
国籍：KR
代理机构：Isarpatent
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