Apparatus for continuously referenced analysis of

专利名称：Apparatus for continuously referenced

analysis of reactive components in solution

发明人：William D. Bostick,Mark S. Denton,Stanley R.

Dinsmore

申请号：US06/062375申请日：19790731公开号：US04263406A公开日：19810421

摘要：A continuously referenced apparatus for measuring the concentration of areactive chemical species in solution comprises in combination conduit means forintroducing a sample solution, means for introducing one or more reactants into asample solution, a reaction zone in fluid communication with said conduit means whereina first chemical reaction occurs between said species and reactants, and a streamseparator disposed within the conduit means for separating the sample solution into asample stream and a reference stream. An enzymatic reactor is disposed in fluidcommunication with only the sample stream wherein a second reaction takes placebetween the said reactants, species, and reactor enzymes causing the consumption orproduction of an indicator species in just the sample stream. Measurement means such asa photometric system are disposed in communication with the sample and referencestreams, and the outputs of the measurement means are compared to provide a blankedmeasurement of the concentration of indicator species. A peristaltic pump is provided toequalize flow through the apparatus by evacuation. The apparatus is particularly suitablefor measurement of isoenzymes in body tissues or fluids.

申请人：THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATESDEPARTMENT OF ENERGY

代理人：Allen H. Uzzell,Stephen D. Hamel,C. Clay Carter

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