专利名称:Lipid-dispersion and process for producing
the same
发明人:YAMAMOTO, TOMOHIRO,YOSHIOKA,
TOSHIHIKO,NANKAI, SHIRO
申请号:EP96303580申请日:19960521公开号:EP0744621A3公开日:19980610
摘要:There is disclosed an aqueous dispersion usable as a standard solution fordetermining lipid levels, having a dispersion form and a particle size which are similar tothose of serum lipids. A lipid-containing dispersion is obtained by evaporating an organicsolvent from a mixture prepared by adding cholesterol, a phospholipid, a bile acid or bileacid salt, and a neutral lipid and/or a cholesterol ester in the organic solvent, swelling theresultant thin-film like mixture with water or buffer heated at a temperature higher thana phase transition temperature of the lecithin, and then dispersing the solution by aphysical shear force. There can be easily obtained a solution having a cholesterolconcentration of about less than 1,000 mg/dl, which is extremely stable and can bestored for a long period of time.
申请人:MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD.
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