1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PRO

专利名称：1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE

DERIVATIVES, PROCESSES OF PREPARATIONAND USE AS THERAPEUTICAL AGENTS

发明人：CLEGG, Lawrence, Stephen The Boots

Company PLC,HUNNEYBALL, Ian, MichaelThe Boots Company PLC,JONES, Colin,Gerhart, Pryce,RAFFERTY, Paul The BootsCompany PLC,STEELE, Leslie The BootsCompany PLC

申请号：EP93901678.0申请日：19921212公开号：EP06107A1公开日：19941012

摘要： The invention relates to compounds of formula (I) and their pharmaceuticallyacceptable salts wherein R1, R2 and R3 independently represent hydrogen, halo, alkyl,alkoxy, phenoxy, phenyl, alkoxycarbonyl, - NR13R14, halogenated alkoxy, halogenatedalkyl, benzyloxy, hydroxy, hydroxyalkyl, (C2-6 alkoxycarbonyl) vinyl, -S (O) nR7,carbamoylalkyl, an alkoxycarbonylalkyl, -CONR11R12, or R1 and R2 together with thecarbon atom represent a C3-6 cycloalkyl; R6 represents hydrogen, alkyl or omega-hydroxy alkyl; A represents an alkylene; R8 represents hydrogen, alkyl, halo, alkoxy,hydroxyalkyl, benzyl or phenyl; R9 and R10 independently represent hydrogen, alkyl,halo, alkoxy, phenyl, hydroxyalkyl, alkoxycarbonyl, nitro, NR30R31, a alcanoyloxyalcoyle,or aminomethyl. These compounds have anti-inflammatory and anti-allergic. Also

disclosed are compositions containing the compounds.

申请人：The Boots Company PLC

地址：1 Thane Road West Nottingham Nottinghamshire NG2 3AA GB

国籍：GB

代理机构：Thacker, Michael Anthony

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