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Methods and compositions for treating viral infect

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专利名称:Methods and compositions for treating viral

infections and guanine acyclic nucleosides

发明人:Howard J. Schaeffer申请号:US05/662900申请日:19760301公开号:US04199574A公开日:19800422

摘要:9-Hydroxyethoxymethyl (and related) derivatives of certain 6-, and 2,6-substituted purines have been discovered to have potent anti- viral activities. Novelcompounds and their pharmaceutically acceptable salts, pharmaceutical formulationcontaining the compounds of this invention, and the treatment of viral infections withthese formulations are all disclosed. 9-(2-hydroxyethoxymethyl) guanine and 2-amino-9-(2- hydroxyethoxymethyl)adenine are examples of especially active compounds of thisinvention.

申请人:BURROUGHS WELLCOME

代理人:Donald Brown

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