专利名称:MEMBRANE PROTEIN INTERACTION
ASSAYS
发明人:PELLETIER, MARC, F.,THOMAS, DAVID, Y.申请号:CA0201718申请日:20021106公开号:WO03040385A3公开日:20031211
摘要:In some aspects, the invention provides systems for analysis of protein-proteininteractions in which the luminal domain of Ire1p, or homologues thereof, is replaced withthe domains of heterologous proteins of interest that then mediate either homo- orheterodimerization of the chimeric fusion proteins to activate a reporter system that maybe based on the unfolded protein response pathway (similar to the native activity ofIre1p).
申请人:MCGILL UNIVERSITY,PELLETIER, MARC, F.,THOMAS, DAVID, Y.
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