Identification, Monitoring and Treatment of Diseas

专利名称：Identification, Monitoring and Treatment of

Disease and Characterization of BiologicalCondition Using Gene Expression Profiles

发明人：Michael P. Bevilacqua,John C. Cheronis,Victor

Tryon,Danute M. Bankaitis-Davis

申请号：US12609578申请日：20091030

公开号：US20100086935A1公开日：20100408

摘要：A method provides an index that is indicative of the state of a subject, as to abiological condition, based on a sample from the subject. An embodiment of this methodincludes: deriving from the sample a profile data set, the profile data set including aplurality of members, each member being a quantitative measure of the amount of adistinct RNA or protein constituent in a panel of constituents selected so that

measurement of the constituents enables evaluation of the biological condition; and inderiving the profile data set, achieving such measure for each constituent under

measurement conditions that are substantially repeatable; and applying values from theprofile data set to an index function that provides a mapping from an instance of a profiledata set into a single-valued measure of biological condition, so as to produce an indexpertinent to the biological condition of the subject

申请人：Michael P. Bevilacqua,John C. Cheronis,Victor Tryon,Danute M. Bankaitis-Davis

地址：Boulder CO US,Conifer CO US,Loveland CO US,Longmont CO US

国籍：US,US,US,US

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