NUCLEIC ACID SEQUENCING METHODS AND SYSTEMS

专利名称：NUCLEIC ACID SEQUENCING METHODS AND

SYSTEMS

发明人：Kandaswamy Vijayan,Eugene Tu,Mark A.

Bernard

申请号：US14805381申请日：20150721

公开号：US20170022553A1公开日：20170126

摘要：The present disclosure provides compositions, methods and systems forsequencing a template nucleic acid using a polymerase based, nucleic acid bindingreaction involving examination of the interaction between a polymerase and templatenucleic acid in the presence of one or more unlabeled nucleotides. The methods rely, inpart, on identifying a base of a template nucleic acid during nucleic acid synthesis bycontrolling the sequencing reaction conditions. Template nucleic acid bases may beidentified during an examination step followed by an optional incorporation step.

申请人：Omniome, Inc.

地址：La Jolla CA US

国籍：US

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