专利名称：MODULATION OF ANGIOPOIETIN-LIKE 3
EXPRESSION
发明人：Crooke, Rosanne M.,Graham, Mark J.,Lee,
Richard,Dobie, Kenneth W.
申请号：AU2015200969申请日：20150226
公开号：AU2015200969A1公开日：20150319
摘要：#$%^&*AU2015200969A120150319.pdf##### ABSTRACT Provided herein aremethods, compounds, and compositions for reducing expression of an ANGPTL3 mRNAand protein in an animal. Also provided herein are methods, compounds, and
compositions for reducing plasma lipids, plasma glucose and atherosclerotic plaques inan animal. Such methods, compounds, and compositions are useful to treat, prevent,delay, or ameliorate any one or more of cardiovascular disease or metabolic disease, or asymptom thereof.
申请人：Isis Pharmaceuticals, Inc.
代理人：Pizzeys
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