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Derivatives of eburnamenine, their preparation and

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专利名称:Derivatives of eburnamenine, their

preparation and their therapeuticalapplication

发明人:KOLETAR GABOR, ISTVAN,NAJER,

HENRY,LARDENOIS, PATRICK ANDRELOUIS,LEFEVRE, JEAN PIERRE

申请号:EP78400137.2申请日:19781018公开号:EP0001940A1公开日:19790516

摘要:Derivatives of eburnamenine, of formula: in which R1 = H and R2 = OH or R1 +R2 = additional bond; R3 = COOR4 (with R4 = alkyl containing 2 to 6 carbon atoms or acycloalkyl) or CONR5R6. Or R1 = R2 = H and R3 = COOR7 (with R7 = alkyl containing 1 to6 carbon atoms or a cycloalkyl) or CONR5R6, R5 and R6 = H, alkyl, cycloalkyl or form aheterocyclic radical together with the nitrogen atom. The first stage of their preparationis a bromination. The compounds have an antianoxic and psychotropic activity.

申请人:SYNTHELABO

地址:22, avenue Galilée 92350 Le Plessis-Robinson FR

国籍:FR

代理机构:Thouret-Lemaitre, Elisabeth

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